NR2C1

GENE INFORMATION

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Gene name

NR2C1 (HGNC Symbol)

Synonyms

TR2, TR2-11

Description

Nuclear receptor subfamily 2, group C, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q22

Chromosome location (bp)

95020229 - 95073703

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120798 (version 78.38)

Entrez gene

7181

UniProt

P13056 (UniProt - Evidence at protein level)

neXtProt

NX_P13056

Antibodypedia

NR2C1 antibodies
 

PROTEIN VIEW

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NR2C1-001
 
NR2C1-002
 
NR2C1-004
 
NR2C1-009
 
NR2C1-018
 
NR2C1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NR2C1-001 ENSP00000333275
ENST00000333003
P13056
Show all »
Show » Show » 603 67.3 No 0
NR2C1-002 ENSP00000376813
ENST00000393101
P13056
Show all »
Show » Show » 467 51.2 No 0
NR2C1-004 ENSP00000328843
ENST00000330677
P13056
Show all »
Show » Show » 483 53 No 0
NR2C1-009 ENSP00000446906
ENST00000547469
Show » 16 1.9 No 0
NR2C1-018 ENSP00000450225
ENST00000551647
Show » Show » 73 8.1 No 0
NR2C1-201 ENSP00000478728
ENST00000622476
Show » Show » 434 47.4 No 0