WDR11

GENE INFORMATION

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Gene name

WDR11 (HGNC Symbol)

Synonyms

BRWD2, DR11, FLJ10506, HH14, KIAA1351, WDR15

Description

WD repeat domain 11 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

q26.12

Chromosome location (bp)

120851175 - 120909524

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000120008 (version 78.38)

Entrez gene

55717

UniProt

Q9BZH6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZH6

Antibodypedia

WDR11 antibodies
 

PROTEIN VIEW

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WDR11-001
 
WDR11-016
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WDR11-001 ENSP00000263461
ENST00000263461
Q9BZH6
Show all »
Show » Show » 1224 136.7 No 1
WDR11-016 ENSP00000474880
ENST00000604585
S4R3Z0
Show all »
Show » Show » 312 34.3 No 0