EPCAM

GENE INFORMATION

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Gene name

EPCAM (HGNC Symbol)

Synonyms

17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1

Description

Epithelial cell adhesion molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]

Chromosome

2

Cytoband

p21

Chromosome location (bp)

47345158 - 47387601

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000119888 (version 78.38)

Entrez gene

4072

UniProt

P16422 (UniProt - Evidence at protein level)

neXtProt

NX_P16422

Antibodypedia

EPCAM antibodies
 

PROTEIN VIEW

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EPCAM-001
 
EPCAM-002
 
EPCAM-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPCAM-001 ENSP00000263735
ENST00000263735
P16422
Show all »
Show » Show » 314 34.9 Yes 1
EPCAM-002 ENSP00000385476
ENST00000405271
B5MCA4
Show all »
Show » 342 37.9 No 1
EPCAM-006 ENSP00000389028
ENST00000419334
C9JKY3
Show all »
Show » 199 21 Yes 0