NR4A3

GENE INFORMATION

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Gene name

NR4A3 (HGNC Symbol)

Synonyms

CHN, CSMF, MINOR, NOR1

Description

Nuclear receptor subfamily 4, group A, member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Chromosome

9

Cytoband

q31.1

Chromosome location (bp)

99821855 - 99866891

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000119508 (version 78.38)

Entrez gene

8013

UniProt

Q92570 (UniProt - Evidence at protein level)

neXtProt

NX_Q92570

Antibodypedia

NR4A3 antibodies
 

PROTEIN VIEW

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NR4A3-001
 
NR4A3-002
 
NR4A3-003
 
NR4A3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NR4A3-001 ENSP00000378531
ENST00000395097
Q92570
Show all »
Show » Show » 626 68.2 No 0
NR4A3-002 ENSP00000340301
ENST00000338488
Q92570
Show all »
Show » Show » 443 47.8 No 0
NR4A3-003 ENSP00000333122
ENST00000330847
Q92570
Show all »
Show » Show » 637 69.5 No 0
NR4A3-201 ENSP00000482027
ENST00000618101
Q92570
Show all »
Show » Show » 637 69.5 No 0