FGF23

GENE INFORMATION

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Gene name

FGF23

Synonyms

Description

Fibroblast growth factor 23 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the fibroblast growth factor family of proteins, which possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. The product of this gene regulates phosphate homeostasis and transport in the kidney. The full-length, functional protein may be deactivated via cleavage into N-terminal and C-terminal chains. Mutation of this cleavage site causes autosomal dominant hypophosphatemic rickets (ADHR). Mutations in this gene are also associated with hyperphosphatemic familial tumoral calcinosis (HFTC). [provided by RefSeq, Feb 2013]

Chromosome

12

Cytoband

p13.32

Chromosome location (bp)

4368227 - 4379728

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118972 (version 78.38)

Entrez gene

8074

UniProt

Q9GZV9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9GZV9

Antibodypedia

FGF23 antibodies
 

PROTEIN VIEW

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FGF23-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF23-001 ENSP00000237837
ENST00000237837
Q9GZV9
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