TGIF2

GENE INFORMATION

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Gene name

TGIF2

Synonyms

Description

TGFB-induced factor homeobox 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor, which appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and over-expressed in some ovarian cancers. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 1. Read-through transcription also exists between this gene and the neighboring downstream C20orf24 (chromosome 20 open reading frame 24) gene. [provided by RefSeq, Dec 2010]

Chromosome

20

Cytoband

q11.23

Chromosome location (bp)

36573488 - 36593950

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118707 (version 78.38)

Entrez gene

60436

UniProt

Q9GZN2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9GZN2

Antibodypedia

TGIF2 antibodies
 

PROTEIN VIEW

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TGIF2-001
 
TGIF2-002
 
TGIF2-003
 
TGIF2-004
 
TGIF2-005
 
TGIF2-006
 
TGIF2-007
 
TGIF2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TGIF2-001 ENSP00000362979
ENST00000373872
Q9GZN2
Show all »
Show » Show » 237 25.9 No 0
TGIF2-002 ENSP00000362981
ENST00000373874
Q9GZN2
Show all »
Show » Show » 237 25.9 No 0
TGIF2-003 ENSP00000453773
ENST00000560025
Q9GZN2
Show all »
Show » Show » 237 25.9 No 0
TGIF2-004 ENSP00000452878
ENST00000558028
H0YKN5
Show all »
Show » Show » 174 18.9 No 0
TGIF2-005 ENSP00000475729
ENST00000561398
Show » Show » 92 10.2 No 0
TGIF2-006 ENSP00000476174
ENST00000557885
Show » Show » 111 13 No 0
TGIF2-007 ENSP00000475479
ENST00000558465
U3KQ25
Show all »
Show » 35 3.7 No 0
TGIF2-201 ENSP00000481787
ENST00000611732
Q9GZN2
Show all »
Show » Show » 237 25.9 No 0