TCF21

GENERAL INFORMATION

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Gene name

TCF21

Gene description

Transcription factor 21

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (placenta)
GTEx:Tissue enhanced (lung)

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression at variable levels with additional nuclear and nucleolar expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Sub cellular location is contradicted by external data. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA013189
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (placenta)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (lung)

Organ

Expression



GENE INFORMATION

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Gene name

TCF21 (HGNC Symbol)

Synonyms

bHLHa23, POD1

Description

Transcription factor 21 (HGNC Symbol)

Entrez gene summary

TCF21 encodes a transcription factor of the basic helix-loop-helix family. The TCF21 product is mesoderm specific, and expressed in embryonic epicardium, mesenchyme-derived tissues of lung, gut, gonad, and both mesenchymal and glomerular epithelial cells in the kidney. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q23.2

Chromosome location (bp)

133889138 - 133895553

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000118526 (version 78.38)

Entrez gene

6943

UniProt

O43680 (UniProt - Evidence at transcript level)

neXtProt

NX_O43680

Antibodypedia

TCF21 antibodies


PROTEIN BROWSER

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ENST00000237316
 
ENST00000367882
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TCF21-001 ENSP00000356857
ENST00000367882
O43680
Show all »
Show » Show » 179 19.7 No 0
TCF21-002 ENSP00000237316
ENST00000237316
O43680
Show all »
Show » Show » 179 19.7 No 0