PLA2G2D

GENE INFORMATION

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Gene name

PLA2G2D (HGNC Symbol)

Synonyms

sPLA2S

Description

Phospholipase A2, group IID (HGNC Symbol)

Entrez gene summary

This gene encodes a secreted member of the phospholipase A2 family, and is found in a cluster of related family members on chromosome 1. Phospholipase A2 family members hydrolyze the sn-2 fatty acid ester bond of glycerophospholipids to produce lysophospholipids and free fatty acid. This gene may be involved in inflammation and immune response, and in weight loss associated with chronic obstructive pulmonary disease. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

Chromosome

1

Cytoband

p36.12

Chromosome location (bp)

20111939 - 20119566

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000117215 (version 78.38)

Entrez gene

26279

UniProt

Q9UNK4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNK4

Antibodypedia

PLA2G2D antibodies
 

PROTEIN VIEW

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PLA2G2D-001
 
PLA2G2D-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLA2G2D-001 ENSP00000364246
ENST00000375105
Q9UNK4
Show all »
Show » Show » 145 16.5 Yes 0
PLA2G2D-201 ENSP00000482871
ENST00000617227
Show » 62 6.6 Yes 0