CRYZ

GENE INFORMATION

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Gene name

CRYZ

Synonyms

Description

Crystallin, zeta (quinone reductase) (HGNC Symbol)

Entrez gene summary

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

Chromosome

1

Cytoband

p31.1

Chromosome location (bp)

74705482 - 74733408

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116791 (version 78.38)

Entrez gene

1429

UniProt

Q08257 (UniProt - Evidence at protein level)

neXtProt

NX_Q08257

Antibodypedia

CRYZ antibodies
 

PROTEIN VIEW

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CRYZ-001
 
CRYZ-002
 
CRYZ-003
 
CRYZ-004
 
CRYZ-005
 
CRYZ-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRYZ-001 ENSP00000339399
ENST00000340866
Q08257
Show all »
Show » Show » 329 35.2 No 0
CRYZ-002 ENSP00000359909
ENST00000370872
Q08257
Show all »
Show » Show » 192 20.4 No 0
CRYZ-003 ENSP00000359907
ENST00000370870
A6NP24
Show all »
Show » Show » 243 26 No 0
CRYZ-004 ENSP00000404289
ENST00000441120
C9JH92
Show all »
Show » Show » 206 21.9 No 0
CRYZ-005 ENSP00000359908
ENST00000370871
Q08257
Show all »
Show » Show » 295 31.5 No 0
CRYZ-201 ENSP00000399805
ENST00000417775
Q08257
Show all »
Show » Show » 329 35.2 No 0