ATP5F1

GENE INFORMATION

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Gene name

ATP5F1

Synonyms

Description

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the b subunit of the proton channel. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p13.2

Chromosome location (bp)

111448864 - 111462773

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116459 (version 78.38)

Entrez gene

515

UniProt

P24539 (UniProt - Evidence at protein level)

neXtProt

NX_P24539

Antibodypedia

ATP5F1 antibodies
 

PROTEIN VIEW

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ATP5F1-001
 
ATP5F1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP5F1-001 ENSP00000358737
ENST00000369722
P24539
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Show » Show » 256 28.9 Yes 0
ATP5F1-005 ENSP00000420366
ENST00000483994
Q5QNZ2
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Show » Show » 195 22.3 No 2