FHL2

GENE INFORMATION

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Gene name

FHL2 (HGNC Symbol)

Synonyms

DRAL, SLIM3

Description

Four and a half LIM domains 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. This protein is thought to have a role in the assembly of extracellular membranes. Also, this gene is down-regulated during transformation of normal myoblasts to rhabdomyosarcoma cells and the encoded protein may function as a link between presenilin-2 and an intracellular signaling pathway. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Aug 2011]

Chromosome

2

Cytoband

q12.2

Chromosome location (bp)

105357712 - 105438513

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115641 (version 78.38)

Entrez gene

2274

UniProt

Q14192 (UniProt - Evidence at protein level)

neXtProt

NX_Q14192

Antibodypedia

FHL2 antibodies
 

PROTEIN VIEW

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FHL2-001
 
FHL2-002
 
FHL2-003
 
FHL2-004
 
FHL2-005
 
FHL2-006
 
FHL2-007
 
FHL2-009
 
FHL2-011
 
FHL2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FHL2-001 ENSP00000386665
ENST00000409807
Q14192
Show all »
Show » Show » 279 32.2 No 0
FHL2-002 ENSP00000344266
ENST00000344213
J3KNW4
Show all »
Show » Show » 389 44.2 No 0
FHL2-003 ENSP00000377021
ENST00000393353
Q14192
Show all »
Show » Show » 279 32.2 No 0
FHL2-004 ENSP00000322909
ENST00000322142
Q14192
Show all »
Show » Show » 279 32.2 No 0
FHL2-005 ENSP00000386633
ENST00000408995
Q14192
Show all »
Show » Show » 279 32.2 No 0
FHL2-006 ENSP00000386892
ENST00000409177
Q6I9R8
Show all »
Show » Show » 395 44.8 No 0
FHL2-007 ENSP00000397083
ENST00000447958
C9J3S8
Show all »
Show » 19 2.3 No 0
FHL2-009 ENSP00000377020
ENST00000393352
Q14192
Show all »
Show » Show » 279 32.2 No 0
FHL2-011 ENSP00000476199
ENST00000607522
U3KQT4
Show all »
Show » Show » 65 7.2 No 0
FHL2-201 ENSP00000350846
ENST00000358129
Q5TM15
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Show » 151 15.9 No 0