GLS

GENE INFORMATION

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Gene name

GLS (HGNC Symbol)

Synonyms

GLS1, KIAA0838

Description

Glutaminase (HGNC Symbol)

Entrez gene summary

This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Chromosome

2

Cytoband

q32.2

Chromosome location (bp)

190880827 - 190965552

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115419 (version 78.38)

Entrez gene

2744

UniProt

O94925 (UniProt - Evidence at protein level)

neXtProt

NX_O94925

Antibodypedia

GLS antibodies
 

PROTEIN VIEW

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GLS-001
 
GLS-002
 
GLS-009
 
GLS-010
 
GLS-011
 
GLS-012
 
GLS-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GLS-001 ENSP00000317379
ENST00000320717
O94925
Show all »
Show » Show » 669 73.5 No 0
GLS-002 ENSP00000340689
ENST00000338435
O94925
Show all »
Show » Show » 598 65.5 No 0
GLS-009 ENSP00000386417
ENST00000409626
B8ZZA8
Show all »
Show » Show » 169 18.6 No 0
GLS-010 ENSP00000395596
ENST00000457316
C9JIJ6
Show all »
Show » Show » 164 18 No 0
GLS-011 ENSP00000387177
ENST00000409428
B7Z509
Show all »
Show » Show » 174 19.9 No 0
GLS-012 ENSP00000387135
ENST00000409215
B8ZZC5
Show all »
Show » Show » 103 11.9 No 0
GLS-013 ENSP00000403329
ENST00000412247
H7C201
Show all »
Show » Show » 182 20.3 Yes 0