CLCN2

GENE INFORMATION

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Gene name

CLCN2 (HGNC Symbol)

Synonyms

ClC-2, CLC2, EJM6

Description

Chloride channel, voltage-sensitive 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]

Chromosome

3

Cytoband

q27.1

Chromosome location (bp)

184346185 - 184361651

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000114859 (version 78.38)

Entrez gene

1181

UniProt

P51788 (UniProt - Evidence at protein level)

neXtProt

NX_P51788

Antibodypedia

CLCN2 antibodies
 

PROTEIN VIEW

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CLCN2-001
 
CLCN2-002
 
CLCN2-003
 
CLCN2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLCN2-001 ENSP00000265593
ENST00000265593
P51788
Show all »
Show » Show » 898 98.5 No >9
CLCN2-002 ENSP00000391928
ENST00000457512
P51788
Show all »
Show » Show » 869 95.4 No >9
CLCN2-003 ENSP00000400425
ENST00000434054
P51788
Show all »
Show » Show » 854 93.6 No >9
CLCN2-004 ENSP00000345056
ENST00000344937
P51788
Show all »
Show » Show » 881 96.8 No >9