SCAP

GENE INFORMATION

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Gene name

SCAP (HGNC Symbol)

Synonyms

KIAA0199

Description

SREBF chaperone (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p21.31

Chromosome location (bp)

47413694 - 47477126

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000114650 (version 78.38)

Entrez gene

22937

UniProt

Q12770 (UniProt - Evidence at protein level)

neXtProt

NX_Q12770

Antibodypedia

SCAP antibodies
 

PROTEIN VIEW

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SCAP-001
 
SCAP-006
 
SCAP-007
 
SCAP-008
 
SCAP-201
 
SCAP-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SCAP-001 ENSP00000265565
ENST00000265565
Q12770
Show all »
Show » Show » 1279 139.7 No 8
SCAP-006 ENSP00000415195
ENST00000448217
C9JFY0
Show all »
Show » 88 9.9 No 1
SCAP-007 ENSP00000408102
ENST00000416847
C9JQ35
Show all »
Show » 136 15.5 No 1
SCAP-008 ENSP00000423419
ENST00000495603
D6RA39
Show all »
Show » 132 15 No 1
SCAP-201 ENSP00000401819
ENST00000428413
Show » Show » 352 38.2 No 2
SCAP-202 ENSP00000438956
ENST00000545718
Show » Show » 905 97.9 No 4