DBN1

GENE INFORMATION

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Gene name

DBN1 (HGNC Symbol)

Synonyms

D0S117E

Description

Drebrin 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q35.3

Chromosome location (bp)

177456608 - 177474401

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113758 (version 78.38)

Entrez gene

1627

UniProt

Q16643 (UniProt - Evidence at protein level)

neXtProt

NX_Q16643

Antibodypedia

DBN1 antibodies
 

PROTEIN VIEW

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DBN1-001
 
DBN1-002
 
DBN1-004
 
DBN1-006
 
DBN1-008
 
DBN1-009
 
DBN1-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DBN1-001 ENSP00000308532
ENST00000309007
Q16643
Show all »
Show » Show » 649 71.4 No 0
DBN1-002 ENSP00000292385
ENST00000292385
Q16643
Show all »
Show » Show » 651 71.6 No 0
DBN1-004 ENSP00000377195
ENST00000393565
Q16643
Show all »
Show » Show » 695 76.3 No 0
DBN1-006 ENSP00000423208
ENST00000512501
D6R9Q9
Show all »
Show » Show » 391 41.4 No 0
DBN1-008 ENSP00000421465
ENST00000514833
D6RFI1
Show all »
Show » Show » 124 13.4 No 0
DBN1-009 ENSP00000422854
ENST00000477391
D6R9W4
Show all »
Show » Show » 317 36.5 No 0
DBN1-011 ENSP00000425546
ENST00000506117
D6RCR4
Show all »
Show » Show » 93 10.1 No 0