HRH2

GENE INFORMATION

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Gene name

HRH2

Synonyms

Description

Histamine receptor H2 (HGNC Symbol)

Entrez gene summary

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Chromosome

5

Cytoband

q35.2

Chromosome location (bp)

175658030 - 175686242

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113749 (version 78.38)

Entrez gene

3274

UniProt

P25021 (UniProt - Evidence at transcript level)

neXtProt

NX_P25021

Antibodypedia

HRH2 antibodies
 

PROTEIN VIEW

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HRH2-001
 
HRH2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HRH2-001 ENSP00000366506
ENST00000377291
P25021
Show all »
Show » Show » 397 44.5 No 7
HRH2-002 ENSP00000231683
ENST00000231683
P25021
Show all »
Show » Show » 359 40.1 No 7