APBB3

GENE INFORMATION

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Gene name

APBB3 (HGNC Symbol)

Synonyms

FE65L2

Description

Amyloid beta (A4) precursor protein-binding, family B, member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

q31.3

Chromosome location (bp)

140558268 - 140593752

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113108 (version 78.38)

Entrez gene

10307

UniProt

O95704 (UniProt - Evidence at protein level)

neXtProt

NX_O95704

Antibodypedia

APBB3 antibodies
 

PROTEIN VIEW

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APBB3-001
 
APBB3-002
 
APBB3-003
 
APBB3-011
 
APBB3-012
 
APBB3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

APBB3-001 ENSP00000349177
ENST00000356738
O95704
Show all »
Show » Show » 491 53 No 0
APBB3-002 ENSP00000346378
ENST00000354402
O95704
Show all »
Show » Show » 493 53.2 No 0
APBB3-003 ENSP00000350171
ENST00000357560
O95704
Show all »
Show » Show » 486 52.6 No 0
APBB3-011 ENSP00000402591
ENST00000412920
O95704
Show all »
Show » Show » 484 52.3 No 0
APBB3-012 ENSP00000424317
ENST00000511201
D6RBA1
Show all »
Show » Show » 337 36.9 No 0
APBB3-201 ENSP00000351389
ENST00000358580
E7EX91
Show all »
Show » Show » 339 37.2 No 0