PHF1

GENE INFORMATION

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Gene name

PHF1 (HGNC Symbol)

Synonyms

MTF2L2, TDRD19C

Description

PHD finger protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Chromosome

6

Cytoband

p21.32

Chromosome location (bp)

33410399 - 33416453

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000112511 (version 78.38)

Entrez gene

5252

UniProt

O43189 (UniProt - Evidence at protein level)

neXtProt

NX_O43189

Antibodypedia

PHF1 antibodies
 

PROTEIN VIEW

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PHF1-001
 
PHF1-002
 
PHF1-005
 
PHF1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PHF1-001 ENSP00000363636
ENST00000374512
O43189
Show all »
Show » Show » 457 49.6 No 0
PHF1-002 ENSP00000363640
ENST00000374516
O43189
Show all »
Show » Show » 567 62.1 No 0
PHF1-005 ENSP00000410494
ENST00000427004
A2AB22
Show all »
Show » Show » 145 15.9 No 0
PHF1-006 ENSP00000392697
ENST00000428274
A2AB23
Show all »
Show » Show » 227 25.1 No 0