OPRM1 - Gene info - The Human Protein Atlas

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OPRM1

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TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

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Gene name	OPRM1 (HGNC Symbol)
Synonyms	MOR1
Description	Opioid receptor, mu 1 (HGNC Symbol)
Entrez gene summary	This gene encodes one of at least three opioid receptors in humans; the mu opioid receptor (MOR). The MOR is the principal target of endogenous opioid peptides and opioid analgesic agents such as beta-endorphin and enkephalins. The MOR also has an important role in dependence to other drugs of abuse, such as nicotine, cocaine, and alcohol via its modulation of the dopamine system. The NM_001008503.2:c.118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. Though the canonical MOR belongs to the superfamily of 7-transmembrane-spanning G-protein-coupled receptors some isoforms of this gene have only 6 transmembrane domains. [provided by RefSeq, Oct 2013]
Chromosome	6
Cytoband	q25.2
Chromosome location (bp)	154010496 - 154246867
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000112038 (version 78.38)
Entrez gene	4988
UniProt	P35372 (UniProt - Evidence at protein level)
neXtProt	NX_P35372
Antibodypedia	OPRM1 antibodies

PROTEIN VIEW

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OPRM1-001		OPRM1-002		OPRM1-003		OPRM1-004		OPRM1-005		OPRM1-006		OPRM1-008		OPRM1-010		OPRM1-012		OPRM1-013		OPRM1-014		OPRM1-016		OPRM1-017		OPRM1-019		OPRM1-020		OPRM1-201

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
OPRM1-001	ENSP00000328264 ENST00000330432	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor C7E9I8 [Target identity:74%; Query identity:100%] Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313\|EMBL:ACT35692.1} Q71V90 [Target identity:68%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	400	44.8	No	7
OPRM1-002	ENSP00000411903 ENST00000428397	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:70%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:29%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	392	44	No	7
OPRM1-003	ENSP00000394624 ENST00000434900	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor C7E9I8 [Target identity:60%; Query identity:100%] Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313\|EMBL:ACT35692.1} Q71V90 [Target identity:55%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:23%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:19%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:19%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:8%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0002438 [acute inflammatory response to antigenic stimulus] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0004985 [opioid receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0005925 [focal adhesion] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007191 [adenylate cyclase-activating dopamine receptor signaling pathway] GO:0007193 [adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0007626 [locomotory behavior] GO:0008285 [negative regulation of cell proliferation] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0019904 [protein domain specific binding] GO:0030425 [dendrite] GO:0031005 [filamin binding] GO:0031635 [adenylate cyclase-inhibiting opioid receptor signaling pathway] GO:0031681 [G-protein beta-subunit binding] GO:0032094 [response to food] GO:0032100 [positive regulation of appetite] GO:0032496 [response to lipopolysaccharide] GO:0032590 [dendrite membrane] GO:0032839 [dendrite cytoplasm] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0042060 [wound healing] GO:0042220 [response to cocaine] GO:0042383 [sarcolemma] GO:0043204 [perikaryon] GO:0043278 [response to morphine] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045121 [membrane raft] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0051930 [regulation of sensory perception of pain] GO:0060079 [regulation of excitatory postsynaptic membrane potential] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:0070848 [response to growth factor] GO:0071315 [cellular response to morphine] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	493	55	No	7
OPRM1-004	ENSP00000430247 ENST00000520282	E7EW71 Show all » « Hide E7EW71 [Target identity:99%; Query identity:100%] Mu-type opioid receptor {ECO:0000313\|Ensembl:ENSP00000430247} B8K2Q5 [Target identity:70%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:58%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:57%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM	Show » « Hide GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007218 [neuropeptide signaling pathway] GO:0016021 [integral component of membrane] GO:0038003 [opioid receptor signaling pathway]	163	17.3	No	1
OPRM1-005	ENSP00000430876 ENST00000520708	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%] Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313\|EMBL:ACT35692.1} Q71V90 [Target identity:91%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} Q7Z6A5 [Target identity:13%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	300	34.4	No	6
OPRM1-006	ENSP00000430260 ENST00000518759	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor C7E9I8 [Target identity:93%; Query identity:100%] Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313\|EMBL:ACT35692.1} Q71V90 [Target identity:86%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} Q7Z6A5 [Target identity:12%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	319	36.5	No	5
OPRM1-008	ENSP00000338381 ENST00000337049	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:65%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:27%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:22%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:22%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:9%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	418	47	No	7
OPRM1-010	ENSP00000410497 ENST00000452687	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:67%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	406	45.5	No	7
OPRM1-012	ENSP00000229768 ENST00000229768	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:61%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:25%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:21%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:21%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:9%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	446	49.5	No	7
OPRM1-013	ENSP00000403549 ENST00000419506	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:65%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:27%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:22%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:22%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:9%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	420	47.1	No	7
OPRM1-014	ENSP00000430097 ENST00000524163	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:70%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:29%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:24%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	389	43.6	No	7
OPRM1-016	ENSP00000399359 ENST00000414028	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:68%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	403	44.9	No	7
OPRM1-017	ENSP00000413752 ENST00000435918	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor Q71V90 [Target identity:69%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	397	44.7	No	7
OPRM1-019	ENSP00000429719 ENST00000522555	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%] Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313\|EMBL:ACT35692.1} Q71V90 [Target identity:91%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} Q7Z6A5 [Target identity:13%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	300	34.4	No	6
OPRM1-020	ENSP00000429373 ENST00000522236	P35372 Show all » « Hide P35372 [Direct mapping] Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%] Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313\|EMBL:ACT35692.1} Q71V90 [Target identity:91%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} Q7Z6A5 [Target identity:13%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM FDA approved drug targets Small molecule drugs	Show » « Hide GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]	300	34.4	No	6
OPRM1-201	ENSP00000353598 ENST00000360422	L0E130 Show all » « Hide L0E130 [Target identity:100%; Query identity:100%] Micro opioid receptor isoform hMOR-1A2 {ECO:0000313\|EMBL:AGA35553.1} Q71V90 [Target identity:57%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAC51878.1} B8K2Q5 [Target identity:24%; Query identity:100%] Mu opioid receptor splice variant MOR-1H {ECO:0000313\|EMBL:ABH03503.1} C9E9Z9 [Target identity:20%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85685.1} C9EA00 [Target identity:19%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:ACV85686.1} Q7Z6A5 [Target identity:8%; Query identity:100%] Mu opioid receptor {ECO:0000313\|EMBL:AAP58255.1}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM	Show » « Hide GO:0004930 [G-protein coupled receptor activity] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane]	476	53.3	No	7

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.