TPI1

GENE INFORMATION

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Gene name

TPI1

Synonyms

Description

Triosephosphate isomerase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme, consisting of two identical proteins, which catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in glycolysis and gluconeogenesis. Mutations in this gene are associated with triosephosphate isomerase deficiency. Pseudogenes have been identified on chromosomes 1, 4, 6 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

6867119 - 6870948

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111669 (version 78.38)

Entrez gene

7167

UniProt

P60174 (UniProt - Evidence at protein level)

neXtProt

NX_P60174

Antibodypedia

TPI1 antibodies
 

PROTEIN VIEW

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TPI1-001
 
TPI1-002
 
TPI1-003
 
TPI1-004
 
TPI1-005
 
TPI1-008
 
TPI1-201
 
TPI1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TPI1-001 ENSP00000229270
ENST00000229270
P60174
Show all »
Show » Show » 286 30.8 No 0
TPI1-002 ENSP00000475620
ENST00000488464
P60174
Show all »
Show » Show » 167 18 No 0
TPI1-003 ENSP00000475364
ENST00000493987
U3KPZ0
Show all »
Show » Show » 113 12.4 No 0
TPI1-004 ENSP00000475184
ENST00000462761
U3KPS5
Show all »
Show » Show » 39 4.2 No 0
TPI1-005 ENSP00000475829
ENST00000495834
U3KQF3
Show all »
Show » Show » 98 10.6 No 0
TPI1-008 ENSP00000379933
ENST00000396705
P60174
Show all »
Show » Show » 249 26.7 No 0
TPI1-201 ENSP00000443599
ENST00000535434
P60174
Show all »
Show » Show » 167 18 No 0
TPI1-202 ENSP00000484435
ENST00000613953
P60174
Show all »
Show » Show » 286 30.8 No 0