IFNG

GENERAL INFORMATION

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Gene name

IFNG

Gene description

Interferon, gamma

Protein class

Cancer-related genes
Disease related genes
FDA approved drug targets
Plasma proteins
Predicted secreted proteins

Predicted localization

Secreted

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (bone marrow, lymph node)
GTEx:Tissue enhanced (lung)

Protein evidence

Evidence at protein level

Protein localization

Distinct plasma staining.

ANTIBODY RELIABILITY

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Data reliability
description

Secreted protein, tissue location of RNA and protein might differ and correlation is complex. External characterization data supports antibody staining.

Data reliability

Uncertain based on 1 antibody.
CAB010344
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (bone marrow, lymph node)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (lung)

Organ

Expression



GENE INFORMATION

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Gene name

IFNG

Synonyms

Description

Interferon, gamma (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the type II interferon family. The protein encoded is a soluble cytokine with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. Mutations in this gene are associated with aplastic anemia.[provided by RefSeq, Nov 2009]

Chromosome

12

Cytoband

q15

Chromosome location (bp)

68154768 - 68159747

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000111537 (version 78.38)

Entrez gene

3458

UniProt

P01579 (UniProt - Evidence at protein level)

neXtProt

NX_P01579

Antibodypedia

IFNG antibodies


PROTEIN BROWSER

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ENST00000229135
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IFNG-001 ENSP00000229135
ENST00000229135
P01579
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