DAO

GENE INFORMATION

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Gene name

DAO (HGNC Symbol)

Synonyms

DAMOX

Description

D-amino-acid oxidase (HGNC Symbol)

Entrez gene summary

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

q24.11

Chromosome location (bp)

108858932 - 108901043

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110887 (version 78.38)

Entrez gene

1610

UniProt

P14920 (UniProt - Evidence at protein level)

neXtProt

NX_P14920

Antibodypedia

DAO antibodies
 

PROTEIN VIEW

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DAO-001
 
DAO-006
 
DAO-008
 
DAO-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DAO-001 ENSP00000228476
ENST00000228476
P14920
Show all »
Show » Show » 347 39.5 No 0
DAO-006 ENSP00000446853
ENST00000551281
Show » Show » 281 31.5 Yes 0
DAO-008 ENSP00000449967
ENST00000547768
F8VV35
Show all »
Show » Show » 167 19.3 No 0
DAO-009 ENSP00000447104
ENST00000547166
F8W152
Show all »
Show » Show » 197 22.4 No 0