FOLR3

GENE INFORMATION

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Gene name

FOLR3 (HGNC Symbol)

Synonyms

FR-G

Description

Folate receptor 3 (gamma) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

q13.4

Chromosome location (bp)

72114869 - 72139892

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000110203 (version 78.38)

Entrez gene

2352

UniProt

P41439 (UniProt - Evidence at protein level)

neXtProt

NX_P41439

Antibodypedia

FOLR3 antibodies
 

PROTEIN VIEW

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FOLR3-002
 
FOLR3-003
 
FOLR3-004
 
FOLR3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FOLR3-002 ENSP00000481114
ENST00000611028
J3KQY0
Show all »
Show » Show » 245 27.9 Yes 0
FOLR3-003 ENSP00000481833
ENST00000622388
F5H2G8
Show all »
Show » 178 20.6 Yes 0
FOLR3-004 ENSP00000446279
ENST00000546166
F5H2G8
Show all »
Show » 74 8.2 Yes 0
FOLR3-201 ENSP00000411161
ENST00000442948
P41439
Show all »
Show » Show » 104 11.8 Yes 0