NEIL3

GENE INFORMATION

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Gene name

NEIL3 (HGNC Symbol)

Synonyms

FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3

Description

Nei endonuclease VIII-like 3 (E. coli) (HGNC Symbol)

Entrez gene summary

NEIL3 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).[supplied by OMIM, Mar 2008]

Chromosome

4

Cytoband

q34.3

Chromosome location (bp)

177309836 - 177362943

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000109674 (version 78.38)

Entrez gene

55247

UniProt

Q8TAT5 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TAT5

Antibodypedia

NEIL3 antibodies
 

PROTEIN VIEW

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NEIL3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEIL3-001 ENSP00000264596
ENST00000264596
Q8TAT5
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