HLF

GENE INFORMATION

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Gene name

HLF (HGNC Symbol)

Synonyms

MGC33822

Description

Hepatic leukemia factor (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q22

Chromosome location (bp)

55265012 - 55325065

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000108924 (version 78.38)

Entrez gene

3131

UniProt

Q16534 (UniProt - Evidence at transcript level)

neXtProt

NX_Q16534

Antibodypedia

HLF antibodies
 

PROTEIN VIEW

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HLF-001
 
HLF-002
 
HLF-003
 
HLF-005
 
HLF-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HLF-001 ENSP00000226067
ENST00000226067
Q16534
Show all »
Show » Show » 295 33.2 No 0
HLF-002 ENSP00000402496
ENST00000430986
Q16534
Show all »
Show » Show » 210 23.5 No 0
HLF-003 ENSP00000460296
ENST00000573945
Q16534
Show all »
Show » Show » 210 23.5 No 0
HLF-005 ENSP00000460572
ENST00000575345
Q16534
Show all »
Show » Show » 210 23.5 No 0
HLF-011 ENSP00000461455
ENST00000572002
I3L4R4
Show all »
Show » Show » 236 26.5 No 0