ABCC3

GENE INFORMATION

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Gene name

ABCC3 (HGNC Symbol)

Synonyms

cMOAT2, EST90757, MLP2, MOAT-D, MRP3

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.33

Chromosome location (bp)

50634777 - 50692252

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108846 (version 78.38)

Entrez gene

8714

UniProt

O15438 (UniProt - Evidence at protein level)

neXtProt

NX_O15438

Antibodypedia

ABCC3 antibodies
 

PROTEIN VIEW

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ABCC3-001
 
ABCC3-002
 
ABCC3-006
 
ABCC3-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC3-001 ENSP00000285238
ENST00000285238
O15438
Show all »
Show » Show » 1527 169.3 No >9
ABCC3-002 ENSP00000395160
ENST00000427699
O15438
Show all »
Show » Show » 572 64.6 No >9
ABCC3-006 ENSP00000422786
ENST00000515707
D6RAB7
Show all »
Show » 76 8.2 No 0
ABCC3-013 ENSP00000421755
ENST00000513745
Show » Show » 300 32.8 No 2