SGCA

GENE INFORMATION

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Gene name

SGCA (HGNC Symbol)

Synonyms

A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1

Description

Sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (HGNC Symbol)

Entrez gene summary

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Chromosome

17

Cytoband

q21.33

Chromosome location (bp)

50164214 - 50175931

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108823 (version 78.38)

Entrez gene

6442

UniProt

Q16586 (UniProt - Evidence at protein level)

neXtProt

NX_Q16586

Antibodypedia

SGCA antibodies
 

PROTEIN VIEW

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SGCA-001
 
SGCA-002
 
SGCA-008
 
SGCA-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SGCA-001 ENSP00000262018
ENST00000262018
Q16586
Show all »
Show » Show » 387 42.9 Yes 1
SGCA-002 ENSP00000345522
ENST00000344627
Q16586
Show all »
Show » Show » 263 29.4 Yes 0
SGCA-008 ENSP00000426104
ENST00000511303
H7C5V0
Show all »
Show » Show » 196 21.4 No 0
SGCA-011 ENSP00000422030
ENST00000504073
Show » Show » 160 17.7 No 1