LGALS3BP

GENE INFORMATION

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Gene name

LGALS3BP (HGNC Symbol)

Synonyms

90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B

Description

Lectin, galactoside-binding, soluble, 3 binding protein (HGNC Symbol)

Entrez gene summary

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.3

Chromosome location (bp)

78971238 - 78980109

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108679 (version 78.38)

Entrez gene

3959

UniProt

Q08380 (UniProt - Evidence at protein level)

neXtProt

NX_Q08380

Antibodypedia

LGALS3BP antibodies
 

PROTEIN VIEW

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LGALS3BP-001
 
LGALS3BP-007
 
LGALS3BP-010
 
LGALS3BP-017
 
LGALS3BP-018
 
LGALS3BP-020
 
LGALS3BP-021
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LGALS3BP-001 ENSP00000262776
ENST00000262776
Q08380
Show all »
Show » Show » 585 65.3 Yes 0
LGALS3BP-007 ENSP00000465120
ENST00000591778
K7EJD3
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Show » Show » 205 22 Yes 0
LGALS3BP-010 ENSP00000465380
ENST00000589906
K7EJY8
Show all »
Show » Show » 144 15.6 Yes 0
LGALS3BP-017 ENSP00000468586
ENST00000591274
K7ES75
Show all »
Show » Show » 88 9.5 Yes 0
LGALS3BP-018 ENSP00000468774
ENST00000589775
K7ESM3
Show all »
Show » Show » 209 22.5 Yes 0
LGALS3BP-020 ENSP00000467211
ENST00000589527
K7EP36
Show all »
Show » Show » 259 28.3 Yes 0
LGALS3BP-021 ENSP00000465729
ENST00000585407
K7EKQ5
Show all »
Show » Show » 210 22.7 Yes 0