EBF3

GENE INFORMATION

? »

Gene name

EBF3 (HGNC Symbol)

Synonyms

COE3, DKFZp667B0210

Description

Early B-cell factor 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma. [provided by RefSeq, Sep 2011]

Chromosome

10

Cytoband

q26.3

Chromosome location (bp)

129835283 - 129963841

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108001 (version 78.38)

Entrez gene

253738

UniProt

Q9H4W6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H4W6

Antibodypedia

EBF3 antibodies
 

PROTEIN VIEW

? »
 
 
 
EBF3-001
 
EBF3-002
 
EBF3-004
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EBF3-001 ENSP00000347463
ENST00000355311
Q9H4W6
Show all »
Show » Show » 596 64.9 No 0
EBF3-002 ENSP00000357637
ENST00000368648
Q9H4W6
Show all »
Show » Show » 551 60.4 No 0
EBF3-004 ENSP00000387543
ENST00000440978
Show » 191 19.4 No 0