TYRP1

GENE INFORMATION

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Gene name

TYRP1 (HGNC Symbol)

Synonyms

b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP

Description

Tyrosinase-related protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq, Mar 2009]

Chromosome

9

Cytoband

p23

Chromosome location (bp)

12685439 - 12710290

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107165 (version 78.38)

Entrez gene

7306

UniProt

P17643 (UniProt - Evidence at protein level)

neXtProt

NX_P17643

Antibodypedia

TYRP1 antibodies
 

PROTEIN VIEW

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TYRP1-001
 
TYRP1-002
 
TYRP1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TYRP1-001 ENSP00000373570
ENST00000388918
P17643
Show all »
Show » Show » 537 60.7 Yes 1
TYRP1-002 ENSP00000370528
ENST00000381136
E7EQI3
Show all »
Show » Show » 247 27.7 No 1
TYRP1-005 ENSP00000419006
ENST00000473763
C9JZ52
Show all »
Show » Show » 102 11.3 Yes 0