OGN

GENERAL INFORMATION

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Gene name

OGN

Gene description

Osteoglycin

Protein class

Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (gallbladder)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

A majority of normal cells were weakly stained or negative. The gastrointestinal tract, gall bladder and epididymis showed moderate luminal membranous positivity.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA013132
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (gallbladder)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

OGN (HGNC Symbol)

Synonyms

mimecan, OIF, SLRR3A

Description

Osteoglycin (HGNC Symbol)

Entrez gene summary

This gene encodes a protein which induces ectopic bone formation in conjunction with transforming growth factor beta. This protein is a small proteoglycan which contains tandem leucine-rich repeats (LRR). Alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q22.31

Chromosome location (bp)

92383967 - 92404696

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106809 (version 78.38)

Entrez gene

4969

UniProt

P20774 (UniProt - Evidence at protein level)

neXtProt

NX_P20774

Antibodypedia

OGN antibodies


PROTEIN BROWSER

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ENST00000262551
 
ENST00000375561
 
ENST00000447356
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OGN-001 ENSP00000364711
ENST00000375561
P20774
Show all »
Show » Show » 298 33.9 Yes 0
OGN-002 ENSP00000262551
ENST00000262551
P20774
Show all »
Show » Show » 298 33.9 Yes 0
OGN-003 ENSP00000396709
ENST00000447356
Q5TBF5
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Show » Show » 268 30.5 No 0