CORO2A

GENE INFORMATION

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Gene name

CORO2A (HGNC Symbol)

Synonyms

IR10, WDR2

Description

Coronin, actin binding protein, 2A (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q22.33

Chromosome location (bp)

98120975 - 98192640

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106789 (version 78.38)

Entrez gene

7464

UniProt

Q92828 (UniProt - Evidence at transcript level)

neXtProt

NX_Q92828

Antibodypedia

CORO2A antibodies
 

PROTEIN VIEW

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CORO2A-001
 
CORO2A-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CORO2A-001 ENSP00000343746
ENST00000343933
Q92828
Show all »
Show » Show » 525 59.8 No 0
CORO2A-002 ENSP00000364218
ENST00000375077
Q92828
Show all »
Show » Show » 525 59.8 No 0