CAV2

GENE INFORMATION

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Gene name

CAV2 (HGNC Symbol)

Synonyms

CAV

Description

Caveolin 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]

Chromosome

7

Cytoband

q31.2

Chromosome location (bp)

116287380 - 116508541

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105971 (version 78.38)

Entrez gene

858

UniProt

P51636 (UniProt - Evidence at protein level)

neXtProt

NX_P51636

Antibodypedia

CAV2 antibodies
 

PROTEIN VIEW

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CAV2-001
 
CAV2-019
 
CAV2-023
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAV2-001 ENSP00000222693
ENST00000222693
P51636
Show all »
Show » Show » 162 18.3 No 1
CAV2-019 ENSP00000345679
ENST00000343213
P51636
Show all »
Show » Show » 112 12.8 No 0
CAV2-023 ENSP00000377120
ENST00000393480
E9PCT3
Show all »
Show » Show » 113 13 No 1