TFEC

GENE INFORMATION

? »

Gene name

TFEC (HGNC Symbol)

Synonyms

bHLHe34, TCFEC, TFECL

Description

Transcription factor EC (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

Chromosome

7

Cytoband

q31.2

Chromosome location (bp)

115935148 - 116159896

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105967 (version 78.38)

Entrez gene

22797

UniProt

O14948 (UniProt - Evidence at protein level)

neXtProt

NX_O14948

Antibodypedia

TFEC antibodies
 

PROTEIN VIEW

? »
 
 
 
TFEC-001
 
TFEC-002
 
TFEC-007
 
TFEC-008
 
TFEC-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TFEC-001 ENSP00000265440
ENST00000265440
O14948
Show all »
Show » Show » 347 38.8 No 0
TFEC-002 ENSP00000377125
ENST00000393485
O14948
Show all »
Show » Show » 197 22.7 No 0
TFEC-007 ENSP00000318676
ENST00000320239
O14948
Show all »
Show » Show » 318 35.5 No 0
TFEC-008 ENSP00000417432
ENST00000484212
B7Z757
Show all »
Show » Show » 316 36.4 No 0
TFEC-201 ENSP00000387650
ENST00000457268
O14948
Show all »
Show » Show » 280 31.6 No 0