GSK3A

GENERAL INFORMATION

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Gene name

GSK3A

Gene description

Glycogen synthase kinase 3 alpha

Protein class

Cancer-related genes
Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA028423 , CAB004422
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

GSK3A

Synonyms

Description

Glycogen synthase kinase 3 alpha (HGNC Symbol)

Entrez gene summary

This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

42230186 - 42242625

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105723 (version 78.38)

Entrez gene

2931

UniProt

P49840 (UniProt - Evidence at protein level)

neXtProt

NX_P49840

Antibodypedia

GSK3A antibodies


PROTEIN BROWSER

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ENST00000222330
 
ENST00000398249
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GSK3A-001 ENSP00000222330
ENST00000222330
P49840
Show all »
Show » Show » 483 51 No 0
GSK3A-002 ENSP00000381301
ENST00000398249
A8MT37
Show all »
Show » Show » 401 44.9 No 0