PBX4

GENERAL INFORMATION

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Gene name

PBX4

Gene description

Pre-B-cell leukemia homeobox 4

Protein class

Plasma proteins
Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (testis, thyroid gland)
GTEx:Tissue enhanced (thyroid gland)

Protein evidence

Evidence at transcript level

Protein localization

Membranous expression in a subset of cells in seminiferus ducts in testis.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA049859
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (testis, thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (thyroid gland)

Organ

Expression



GENE INFORMATION

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Gene name

PBX4

Synonyms

Description

Pre-B-cell leukemia homeobox 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the pre-B cell leukemia transcription factor family. These proteins are homeobox proteins that play critical roles in embryonic development and cellular differentiation both as Hox cofactors and through Hox-independent pathways. The encoded protein contains a homeobox DNA-binding domain, but specific functions of the protein have not been determined. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011]

Chromosome

19

Cytoband

p13.11

Chromosome location (bp)

19561707 - 19618916

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000105717 (version 78.38)

Entrez gene

80714

UniProt

Q9BYU1 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BYU1

Antibodypedia

PBX4 antibodies


PROTEIN BROWSER

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ENST00000251203
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PBX4-001 ENSP00000251203
ENST00000251203
Q9BYU1
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