PLIN3

GENE INFORMATION

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Gene name

PLIN3 (HGNC Symbol)

Synonyms

M6PRBP1, PP17, TIP47

Description

Perilipin 3 (HGNC Symbol)

Entrez gene summary

Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2009]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

4838341 - 4867768

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000105355 (version 78.38)

Entrez gene

10226

UniProt

O60664 (UniProt - Evidence at protein level)

neXtProt

NX_O60664

Antibodypedia

PLIN3 antibodies
 

PROTEIN VIEW

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PLIN3-001
 
PLIN3-002
 
PLIN3-003
 
PLIN3-004
 
PLIN3-005
 
PLIN3-007
 
PLIN3-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLIN3-001 ENSP00000221957
ENST00000221957
O60664
Show all »
Show » Show » 434 47.1 No 0
PLIN3-002 ENSP00000468096
ENST00000589494
K7ER39
Show all »
Show » 168 17.6 No 0
PLIN3-003 ENSP00000465117
ENST00000587462
K7EJD0
Show all »
Show » 35 3.6 No 0
PLIN3-004 ENSP00000465975
ENST00000589034
K7EL96
Show all »
Show » 173 18.1 No 0
PLIN3-005 ENSP00000468476
ENST00000589163
Show » 292 31.9 No 0
PLIN3-007 ENSP00000467803
ENST00000592528
O60664
Show all »
Show » Show » 422 45.8 No 0
PLIN3-008 ENSP00000465596
ENST00000585479
O60664
Show all »
Show » Show » 433 46.9 No 0