AES

GENERAL INFORMATION

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Gene name

AES

Gene description

Amino-terminal enhancer of split

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

AES (HGNC Symbol)

Synonyms

GRG5, TLE5

Description

Amino-terminal enhancer of split (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

3052910 - 3063107

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104964 (version 78.38)

Entrez gene

166

UniProt

Q08117 (UniProt - Evidence at protein level)

neXtProt

NX_Q08117

Antibodypedia

AES antibodies


PROTEIN BROWSER

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ENST00000221561
 
ENST00000327141
 
ENST00000586742
 
ENST00000586839
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AES-001 ENSP00000221561
ENST00000221561
Q08117
Show all »
Show » Show » 264 29.1 No 0
AES-003 ENSP00000317537
ENST00000327141
Q08117
Show all »
Show » Show » 197 22 No 0
AES-004 ENSP00000466038
ENST00000586742
Show » Show » 264 28.6 No 0
AES-009 ENSP00000467831
ENST00000586839
K7EQH5
Show all »
Show » Show » 141 15.5 No 0