RIPK2

GENE INFORMATION

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Gene name

RIPK2 (HGNC Symbol)

Synonyms

CARD3, CARDIAK, RICK, RIP2

Description

Receptor-interacting serine-threonine kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

q21.3

Chromosome location (bp)

89757747 - 89791063

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000104312 (version 78.38)

Entrez gene

8767

UniProt

O43353 (UniProt - Evidence at protein level)

neXtProt

NX_O43353

Antibodypedia

RIPK2 antibodies
 

PROTEIN VIEW

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RIPK2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RIPK2-001 ENSP00000220751
ENST00000220751
O43353
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