LACTB

GENE INFORMATION

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Gene name

LACTB (HGNC Symbol)

Synonyms

FLJ14902, MRPL56

Description

Lactamase, beta (HGNC Symbol)

Entrez gene summary

This gene encodes a mitochondrially-localized protein that has sequence similarity to prokaryotic beta-lactamases. Many of the residues responsible for beta-lactamase activity are not conserved in this protein, suggesting it may have a different enzymatic function. Increased expression of the related mouse gene was found to be associated with obesity. Alternative splicing results in multiple transcript variants encoding different protein isoforms. [provided by RefSeq, Dec 2013]

Chromosome

15

Cytoband

q22.2

Chromosome location (bp)

63121800 - 63142061

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103642 (version 78.38)

Entrez gene

114294

UniProt

P83111 (UniProt - Evidence at protein level)

neXtProt

NX_P83111

Antibodypedia

LACTB antibodies
 

PROTEIN VIEW

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LACTB-001
 
LACTB-002
 
LACTB-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LACTB-001 ENSP00000261893
ENST00000261893
P83111
Show all »
Show » Show » 547 60.7 Yes 0
LACTB-002 ENSP00000392956
ENST00000413507
P83111
Show all »
Show » Show » 373 41.2 Yes 0
LACTB-003 ENSP00000454085
ENST00000557972
H0YNN5
Show all »
Show » 126 14.6 No 0