CRYM

GENE INFORMATION

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Gene name

CRYM (HGNC Symbol)

Synonyms

DFNA40

Description

Crystallin, mu (HGNC Symbol)

Entrez gene summary

Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]

Chromosome

16

Cytoband

p12.2

Chromosome location (bp)

21238874 - 21303083

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103316 (version 78.38)

Entrez gene

1428

UniProt

Q14894 (UniProt - Evidence at protein level)

neXtProt

NX_Q14894

Antibodypedia

CRYM antibodies
 

PROTEIN VIEW

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CRYM-001
 
CRYM-003
 
CRYM-004
 
CRYM-005
 
CRYM-006
 
CRYM-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CRYM-001 ENSP00000219599
ENST00000219599
Q14894
Show all »
Show » Show » 314 33.8 No 0
CRYM-003 ENSP00000460820
ENST00000570401
Show » 97 10.4 No 0
CRYM-004 ENSP00000460126
ENST00000576703
I3L325
Show all »
Show » Show » 241 26.1 No 0
CRYM-005 ENSP00000460510
ENST00000571358
I3L3J9
Show all »
Show » 26 2.8 No 0
CRYM-006 ENSP00000461904
ENST00000572914
I3NI53
Show all »
Show » 140 14.8 No 0
CRYM-201 ENSP00000440227
ENST00000543948
Q14894
Show all »
Show » Show » 314 33.8 No 0