COTL1

GENE INFORMATION

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Gene name

COTL1 (HGNC Symbol)

Synonyms

CLP

Description

Coactosin-like F-actin binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q24.1

Chromosome location (bp)

84565594 - 84618077

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103187 (version 78.38)

Entrez gene

23406

UniProt

Q14019 (UniProt - Evidence at protein level)

neXtProt

NX_Q14019

Antibodypedia

COTL1 antibodies
 

PROTEIN VIEW

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COTL1-001
 
COTL1-002
 
COTL1-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

COTL1-001 ENSP00000262428
ENST00000262428
Q14019
Show all »
Show » Show » 142 15.9 No 0
COTL1-002 ENSP00000457033
ENST00000564057
H3BT58
Show all »
Show » Show » 73 8.2 No 0
COTL1-007 ENSP00000480117
ENST00000567786
Show » 48 5.2 No 0