SGCG

GENE INFORMATION

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Gene name

SGCG (HGNC Symbol)

Synonyms

A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, MGC130048, SCARMD2, SCG3, TYPE

Description

Sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (HGNC Symbol)

Entrez gene summary

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq, Oct 2008]

Chromosome

13

Cytoband

q12.12

Chromosome location (bp)

23180952 - 23325165

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102683 (version 78.38)

Entrez gene

6445

UniProt

Q13326 (UniProt - Evidence at protein level)

neXtProt

NX_Q13326

Antibodypedia

SGCG antibodies
 

PROTEIN VIEW

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SGCG-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SGCG-001 ENSP00000218867
ENST00000218867
Q13326
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