SLC25A14

GENE INFORMATION

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Gene name

SLC25A14 (HGNC Symbol)

Synonyms

BMCP1, UCP5

Description

Solute carrier family 25 (mitochondrial carrier, brain), member 14 (HGNC Symbol)

Entrez gene summary

Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). Uncoupling proteins separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. Uncoupling proteins facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. This gene is widely expressed in many tissues with the greatest abundance in brain and testis. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 4. [provided by RefSeq, Aug 2013]

Chromosome

X

Cytoband

q26.1

Chromosome location (bp)

130339888 - 130373361

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102078 (version 78.38)

Entrez gene

9016

UniProt

O95258 (UniProt - Evidence at transcript level)

neXtProt

NX_O95258

Antibodypedia

SLC25A14 antibodies
 

PROTEIN VIEW

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SLC25A14-001
 
SLC25A14-002
 
SLC25A14-003
 
SLC25A14-004
 
SLC25A14-201
 
SLC25A14-202
 
SLC25A14-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC25A14-001 ENSP00000218197
ENST00000218197
O95258
Show all »
Show » Show » 325 36.2 Yes 0
SLC25A14-002 ENSP00000354455
ENST00000361980
O95258
Show all »
Show » Show » 322 36 Yes 0
SLC25A14-003 ENSP00000342797
ENST00000339231
O95258
Show all »
Show » Show » 353 39.2 Yes 4
SLC25A14-004 ENSP00000402578
ENST00000424447
Q5JY88
Show all »
Show » Show » 198 21.9 Yes 0
SLC25A14-201 ENSP00000445225
ENST00000543953
B4DJN2
Show all »
Show » Show » 290 32.4 No 0
SLC25A14-202 ENSP00000444642
ENST00000545805
O95258
Show all »
Show » Show » 325 36.2 Yes 0
SLC25A14-203 ENSP00000477981
ENST00000612248
O95258
Show all »
Show » Show » 353 39.2 Yes 4