SMARCA1

GENERAL INFORMATION

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Gene name

SMARCA1

Gene description

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Normal tissues were in general negative or displayed weak cytoplasmic positivity. Glial cells showed moderate to strong cytoplasmic and nuclear membranous staining.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA003335
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

SMARCA1 (HGNC Symbol)

Synonyms

ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SWI

Description

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the SWI/SNF family of proteins. The encoded protein is an ATPase which is expressed in diverse tissues and contributes to the chromatin remodeling complex that is involved in transcription. The protein may also play a role in DNA damage, growth inhibition and apoptosis of cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Chromosome

X

Cytoband

Chromosome location (bp)

129446501 - 129523500

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000102038 (version 78.38)

Entrez gene

6594

UniProt

P28370 (UniProt - Evidence at protein level)

neXtProt

NX_P28370

Antibodypedia

SMARCA1 antibodies


PROTEIN BROWSER

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ENST00000371121
 
ENST00000371122
 
ENST00000371123
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMARCA1-004 ENSP00000360163
ENST00000371122
P28370
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Show » Show » 1054 122.6 No 0
SMARCA1-005 ENSP00000360162
ENST00000371121
B7ZLQ5
Show all »
Show » Show » 1070 124.3 No 0
SMARCA1-006 ENSP00000360164
ENST00000371123
Show » Show » 1058 122.9 No 0