GPR143

GENE INFORMATION

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Gene name

GPR143 (HGNC Symbol)

Synonyms

OA1

Description

G protein-coupled receptor 143 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in this gene cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y. [provided by RefSeq, Dec 2009]

Chromosome

X

Cytoband

p22.2

Chromosome location (bp)

9725346 - 9786297

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101850 (version 78.38)

Entrez gene

4935

UniProt

P51810 (UniProt - Evidence at protein level)

neXtProt

NX_P51810

Antibodypedia

GPR143 antibodies
 

PROTEIN VIEW

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GPR143-001
 
GPR143-002
 
GPR143-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GPR143-001 ENSP00000417161
ENST00000467482
P51810
Show all »
Show » Show » 404 43.9 No 7
GPR143-002 ENSP00000390546
ENST00000447366
C9J9N1
Show all »
Show » Show » 287 31.8 No 5
GPR143-003 ENSP00000406138
ENST00000431126
C9J9N1
Show all »
Show » Show » 171 19.4 No 3