MAPRE1

GENE INFORMATION

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Gene name

MAPRE1 (HGNC Symbol)

Synonyms

EB1

Description

Microtubule-associated protein, RP/EB family, member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q11.21

Chromosome location (bp)

32819893 - 32850405

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101367 (version 78.38)

Entrez gene

22919

UniProt

Q15691 (UniProt - Evidence at protein level)

neXtProt

NX_Q15691

Antibodypedia

MAPRE1 antibodies
 

PROTEIN VIEW

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MAPRE1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAPRE1-001 ENSP00000364721
ENST00000375571
Q15691
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