POFUT1

GENE INFORMATION

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Gene name

POFUT1 (HGNC Symbol)

Synonyms

FUT12, KIAA0180, O-Fuc-T, O-FUT

Description

Protein O-fucosyltransferase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q11.21

Chromosome location (bp)

32207880 - 32238667

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101346 (version 78.38)

Entrez gene

23509

UniProt

Q9H488 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H488

Antibodypedia

POFUT1 antibodies
 

PROTEIN VIEW

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POFUT1-004
 
POFUT1-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

POFUT1-004 ENSP00000364902
ENST00000375749
Q9H488
Show all »
Show » Show » 388 44 Yes 0
POFUT1-005 ENSP00000364882
ENST00000375730
Q9H488
Show all »
Show » Show » 194 22.3 Yes 0