PLCB4

GENERAL INFORMATION

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Gene name

PLCB4

Gene description

Phospholipase C, beta 4

Protein class

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (thyroid gland)
GTEx:Tissue enhanced (cerebellum)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (thyroid gland)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum)

Organ

Expression



GENE INFORMATION

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Gene name

PLCB4

Synonyms

Description

Phospholipase C, beta 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]

Chromosome

20

Cytoband

Chromosome location (bp)

9068763 - 9481242

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101333 (version 78.38)

Entrez gene

5332

UniProt

Q15147 (UniProt - Evidence at protein level)

neXtProt

NX_Q15147

Antibodypedia

PLCB4 antibodies


PROTEIN BROWSER

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ENST00000278655
 
ENST00000378473
 
ENST00000378493
 
ENST00000378501
 
ENST00000407043
 
ENST00000414679
 
ENST00000416836
 
ENST00000437503
 
ENST00000441846
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PLCB4-001 ENSP00000367754
ENST00000378493
Q15147
Show all »
Show » Show » 1175 134.5 No 0
PLCB4-002 ENSP00000412982
ENST00000441846
B1AJW3
Show all »
Show » Show » 110 12.4 No 0
PLCB4-004 ENSP00000395753
ENST00000416836
B1AJW1
Show all »
Show » Show » 60 7.2 No 0
PLCB4-007 ENSP00000391614
ENST00000437503
B1AJW2
Show all »
Show » Show » 81 9.4 No 0
PLCB4-008 ENSP00000385805
ENST00000407043
B1AJW4
Show all »
Show » Show » 113 12.8 No 0
PLCB4-011 ENSP00000367762
ENST00000378501
Q15147
Show all »
Show » Show » 1194 136.1 No 0
PLCB4-012 ENSP00000390616
ENST00000414679
Q15147
Show all »
Show » Show » 1187 135.8 No 0
PLCB4-201 ENSP00000278655
ENST00000278655
Q15147
Show all »
Show » Show » 1175 134.5 No 0
PLCB4-202 ENSP00000367734
ENST00000378473
Q15147
Show all »
Show » Show » 1187 135.8 No 0