PDYN

GENE INFORMATION

? »

Gene name

PDYN (HGNC Symbol)

Synonyms

ADCA, PENKB, SCA23

Description

Prodynorphin (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Chromosome

20

Cytoband

p13

Chromosome location (bp)

1978757 - 1994285

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101327 (version 78.38)

Entrez gene

5173

UniProt

P01213 (UniProt - Evidence at protein level)

neXtProt

NX_P01213

Antibodypedia

PDYN antibodies
 

PROTEIN VIEW

? »
 
 
 
PDYN-002
 
PDYN-201
 
PDYN-202
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDYN-002 ENSP00000217305
ENST00000217305
P01213
Show all »
Show » Show » 254 28.4 Yes 0
PDYN-201 ENSP00000440185
ENST00000539905
P01213
Show all »
Show » Show » 254 28.4 Yes 0
PDYN-202 ENSP00000442259
ENST00000540134
P01213
Show all »
Show » Show » 254 28.4 Yes 0